Early Bills vs Patriots Odds and Betting Lines for Crucial Week 16 Matchup

New England Patriots quarterback Mac Jones looking to throw the ball during an NFL game.

New England Patriots quarterback Mac Jones throws during the second half of an NFL football game against the Indianapolis Colts Saturday, Dec. 18, 2021, in Indianapolis. (AP Photo/Aaron Doster)

The Patriots will host the Bills next Sunday, December 26, at Gillette Stadium in Foxborough.
The Patriots are currently 2-point betting favorites.
Continue reading for early odds and predicted line movement.

The New England Patriots will host the Buffalo Bills next Sunday, December 26, in a Week 16 showdown with key playoff implications. Kickoff is scheduled for December 26 at 1:00 p.m. at Gillette Stadium.

Bills vs Patriots Odds


Buffalo Bills
+2 (-110)
Over 44 (-110)

New England Patriots
-2 (-110)
Under 44 (-110)

Odds as of December 19 via DraftKings.

Bill and Patriots Recent Games

The Patriots come into this game following a tough upset loss to the Indianapolis Colts.

Bill Belichick’s team was outplayed in the first half, to the tune of a 17-0 lead for Indianapolis at halftime. A lead which was then extended to 20-0 by the end of the third quarter.

However, Belichick and company fought back, scoring 17 points in the fourth quarter to make it a competitive game.

Mac Jones completed 26 of his 45 passes for 299 yards, along with two touchdowns and two interceptions.

The new-look, post-Brady Patriots arrived to contention sooner than expected, thanks in large part to the excellent rookie season quarterback Mac Jones has been having. Jones, the 15th overall pick out of Alabama in this spring’s NFL draft, has thrown for 3,168 yards so far this season.  Jones has also tossed 18 touchdowns, while throwing 10 interceptions.

In the first matchup between these two teams earlier this month, New England came away with a 14-10 victory in poor weather. Mac Jones only attempted three passes in the game, but he completed two of those three throws for 19 yards, with zero touchdowns and zero interceptions.

Fewest pass attempts in an NFL win since 1️⃣9️⃣7️⃣4️⃣ pic.twitter.com/nFDtxvzL6X

— New England Patriots (@Patriots) December 8, 2021

Damien Harris led the way for New England in that game, carrying the ball 10 times averaging 11.1 yards per carry.

Harris finished the contest with 111 yards on the ground, and he also scored the only touchdown of the game.

Josh Allen has enjoyed an excellent season for Buffalo, asserting himself as an elite quarterback in the league after an excellent season last year. So far this season, Allen has recorded 3,524 passing yards, throwing 28 touchdowns against 11 interceptions.

Back in the endzone!#CARvsBUF | #BillsMafia pic.twitter.com/vLq2ZgTx8e

— Buffalo Bills (@BuffaloBills) December 19, 2021

Buffalo played earlier today against Carolina. The Bills got off to a strong start, going up by two touchdowns and taking a 17-8 lead into halftime.

The Bills then outscored the Titans in both the third and fourth quarters to run away with a 31-14 victory against the Carolina Panthers.

BILLS WIN!!!#CARvsBUF | #BillsMafia pic.twitter.com/dsQ9cl6yNS

— Buffalo Bills (@BuffaloBills) December 19, 2021

Bills vs Patriots Injury News

Damien Harris didn’t play yesterday against the Colts, after having been listed as questionable throughout much of the week.

Although no official news has been released yet suggesting Harris will (or won’t) play next week against Buffalo. Based on his being listed as questionable prior to being downgraded to out it appears there is a chance that Harris will be on the field.

Patriots downgrade RB Damien Harris (hamstring), OL Yodny Cajuste (illness) to OUT vs. Coltshttps://t.co/TZZmKTWvYu pic.twitter.com/6VusUks8vo

— Around The NFL (@AroundTheNFL) December 17, 2021

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Bills vs Patriots Projected Line Movement

I don’t anticipate this line moving significantly barring unexpected news/COVID situations. Despite the Patriots loss last night, the odds have not changed yet.

This game is going to be played in Foxborough, and home-field advantage is typically between two to three points on the spread.

This indicates that oddsmakers likely view this game as a toss-up if played on a neutral field. I wouldn’t be surprised if this line shifts ever so slightly towards Buffalo. They took care of business against an inferior opponent while New England came up short facing a tough test.

The public will likely side with New England. Taking the trendy pick of Bill Belichick and the Patriots striking gold with another quarterback after two decades with Tom Brady, versus a Bills team that has talent and certainly a contender, but has not yet proven it in the playoffs.

Despite being a week 16 matchup, this game has all the makings of a playoff atmosphere, and I think most bettors will be hesitant to go against Belichick.

Look for the spread to settle in around the -1.5 mark for New England, with the spread perhaps ticking up or down a few points depending on weather conditions. Up if good weather, down if bad weather. I don’t anticipate the moneyline changing much at all, at most maybe changing to +105 for Buffalo and -120 for New England.

Author: wpadmin

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